Season 4
8 episodes · premiered Sep 1, 2021
Season 4 of A.P. Bio continues the show's evolution into a high-energy, absurdist ensemble comedy. Released on Peacock, it focuses on Jack Griffin finally embracing his role as a chaotic mentor to his students while navigating his own unresolved family trauma.
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E1 Tornado!
A tornado puts the school on lockdown. The kids write fan fiction about faculty members.
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E2 Sweatpants
Jack has the students form a fake cult to sabotage Principal Durbin's new school uniforms.
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E3 An Oath to Rusty
Jack attempts to get closer with the guys at work. Helen helps Principal Durbin grow a backbone.
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E4 Tons of Rue
Jack tries to expose his allegedly reformed deadbeat dad. A witch shakes up the Whitlock High staff.
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E5 The Perfect Date From Hell
Jack finds out he's his girlfriend's therapy homework. Principal Durbin goes undercover.
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E6 Love, for Lack of a Better Term
Victor sends Ashlanda a risqué photo. Grace and Anthony try to set up Mary and Principal Durbin.
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E7 Malachi
A jealous Jack crashes his girlfriend's dinner with a male friend. Helen rebounds after a breakup.
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E8 The Harvard Pen
Jack's students steal his Harvard pen. Principal Durbin fails the superintendent's inspection.